The inner ear of mammals uses neurosensory cells derived from the embryonic ear for mechanoelectric transduction of vestibular and auditory stimuli (the hair cells) and conducts this information to the brain via sensory neurons. As with most other neurons of mammals, lost hair cells and sensory neurons are not spontaneously replaced and result instead in age‐dependent progressive hearing loss. We review the molecular basis of neurosensory development in the mouse ear to provide a blueprint for possible enhancement of therapeutically useful (...) transformation of stem cells into lost neurosensory cells. We identify several readily available adult sources of stem cells that express, like the ectoderm‐derived ear, genes known to be essential for ear development. Use of these stem cells combined with molecular insights into neurosensory cell specification and proliferation regulation of the ear, might allow for neurosensory regeneration of mammalian ears in the near future. BioEssays 28: 1181–1193, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

There is scarce research on the interaction between psychosocial working conditions and being a target of workplace bullying with individual characteristics as a moderator. We therefore examined 3,363 employees from 60 Danish workplaces to test whether sense of coherence moderates the relationship between the job demand-control model and bullying. This work is exploratory in nature, as no previous study to assess this moderation was found. Hierarchical linear regressions showed that demand-control model was significantly associated with bullying. Sense of coherence displayed (...) a significant though practically negligible moderating effect. This suggests that negative psychosocial working conditions are associated with bullying independently of personal characteristics, at least in terms of sense of coherence. (shrink)

The theoretical and empirical link between leadership and workplace bullying needs further elaboration. The aim of the study is to examine the relationship between quality of leadership and the occurrence of workplace bullying 2 years later. Furthermore, we aim to examine a possible mechanism from leadership to bullying using social community at work as mediator. Using survey data that were collected at two different points in time among 1664 workers from 60 Danish workplaces, we examined the total, direct and indirect (...) effects between quality of leadership and workplace bullying. Our results indicate that quality of leadership plays a role in establishing working conditions that lead to workplace bullying. Furthermore, social community at work fully mediates the effect of poor quality of leadership on workplace bullying. This longitudinal study adds to previous cross-sectional studies on the substantial role played by leaders in the bullying process. Within the leadership–bullying relationship, social community at work acts as a full mediator, adding a significant contribution to the discussion of mechanisms involved in the bullying process. Plausible explanations of this mechanism and practical implications are discussed. (shrink)

Experiential evidence shows that pain is associated with common meanings. These include a meaning of threat or danger, which is experienced as immediately distressing or unpleasant; cognitive meanings, which are focused on the long-term consequences of having chronic pain; and existential meanings such as hopelessness, which are more about the person with chronic pain than the pain itself. This interdisciplinary book - the second in the three-volume Meanings of Pain series edited by Dr Simon van Rysewyk - aims to better (...) understand pain by describing experiences of pain and the meanings these experiences hold for the people living through them. The lived experiences of pain described here involve various types of chronic pain, including spinal pain, labour pain, rheumatic pain, diabetic peripheral neuropathic pain, fibromyalgia, complex regional pain syndrome, endometriosis-associated pain, and cancer-related pain. Two chapters provide narrative descriptions of pain, recounted and interpreted by people with pain. Language is important to understanding the meaning of pain since it is the primary tool human beings use to manipulate meaning. As discussed in the book, linguistic meaning may hold clues to understanding some pain-related experiences, including the stigmatisation of people with pain, the dynamics of patient-clinician communication, and other issues, such as relationships between pain, public policy and the law, and attempts to develop a taxonomy of pain that is meaningful for patients. Clinical implications are described in each chapter. This book is intended for people with pain, their family members or caregivers, clinicians, researchers, advocates, and policy makers. (shrink)

Problem: Medical student mistreatment, as well as patient and staff mistreatment by all levels of medical trainees and faculty, is still prevalent in U.S. clinical training. Largely missing in interventions to reduce mistreatment is acknowledgement of the abuse of power produced by the hierarchical structure in which medicine is practiced. Approach: Beginning in 2001, Yale School of Medicine has held annual “Power Day” workshops for third year medical students and advanced practice nursing students, to define and analyse power dynamics within (...) the medical hierarchy and hidden curriculum using literature, guest speakers, and small groups. During rotations, medical students write narratives about the use of power witnessed in the wards. In response to student and small group leader feedback, workshop organizers have developed additional activities related to examining and changing the use of power in clinical teams. Outcome: Emerging narrative themes included the potential impact of small acts and students feeling “mute” and “complicit” in morally distressing situations. Small groups provided safe spaces for advice, support, and professional identity formation. By 2005, students recognized residents that used power positively with Power Day awards and alumni served as keynote speakers on the use of power in medicine. By 2010, departments including OB/GYN, surgery, psychiatry, and paediatrics, had added weekly team Power Hour discussions. Next Steps: The authors highlight barriers, benefits, and lessons learned. Barriers include the notion of clinical irrelevance and resistance to the word “power” due to perceived accusation of abuse. Benefits include promoting open dialogue about power, fostering inter-professional collaboration, rewarding positive role modelling by residents and faculty, and creating a network of trainee empowerment and leadership. Furthermore, faculty have started to ask that issues of power be addressed in a more transparent way at their level of the hierarchy as well. (shrink)

En este artículo analizaré dos importantes aproximaciones contemporáneas a la democracia ateniense. Se trata de las interpretaciones enfrentadas de dos helenistas que han arrojado nueva luz sobre el conocimiento de la democracia clásica. Mogens H. Hansen se ha centrado especialmente en el estudio de las instituciones como fundamento del poder democrático, mientras Josiah Ober, basándose en los textos retóricos, pretende reconstruir la ideología popular a la que hace responsable del dominio político del dêmos sobre la elite. Intentaré, a su (...) vez, trazar las líneas de filiación teórica de ambas posturas y, para ello, abordaré una segunda cuestión, la de qué es la polis griega, un estado o una sociedad sin estado. Mi conclusión es que la lectura de Hansen está muy cercana a la historiografía liberal de G. Grote, mientras que la de Ober no es ajena a las lecturas antropológicas y comunitaristas. (shrink)

Is Plato’s philosophy still relevant for current issues in politics and political science? In order to answer this question, the contributions to this volume endeavour to re-read the Platonic dialogues and to interpret them in terms of textual hermeneutics on the one hand. On the other hand, they refer to Plato from a systematic point of view and apply his philosophy, in particular the method of Socratic dialogue, to discussions on contemporary political issues. The volume is dedicated to Barbara Zehnpfennig, (...) whose works aim at making Socratic–Platonic philosophy fruitful for the present on the basis of a new interpretation of Plato’s philosophy. With contributions by Anke Adamik, Sarah Al-Taher, Viktoria Bachmann, Philip Breuer, Johanna Falk-Seifert, Bettina Fröhlich, Benjamin A. Hahn, Hendrik Hansen, Thomas Haslböck, Raul Heimann, Johannes Frank Hoerlin, Vanessa Jansche, Peter Kainz, Christina Kast, Eva-Maria Kaufmann, Ulrich Kühn, Laura Martena, Julian Obenauer, Victor Peneff und Thomas Wimmer. (shrink)

THE AMERICAN DREAM INCLUDES OWNING A HOME, ANDTHE BIGGER THE better. Christian responses to homelessness and housing vary. Some Christian organizations focus on fixing the person and the behaviors that contribute to homelessness. Others promote home ownership for low-income households. Employing aspects of Traci West's feminist liberationist ethical methodology, I will assess how these approaches buy into our culture's dominant ideology on housing or offer prophetic disruption. Then I will outline an advocacy approach that addresses the multiple causes of homelessness (...) and prophetically aims to make a home for all in God's compassionate community. (shrink)

This article examines a genetic ancestry testing program called the Living History Project that was jointly organized by a nonprofit educational institute and a for-profit genealogy company in South Africa. It charts the precise mechanisms by which the LHP sought to shape a postapartheid genome through antiracist commitments aimed at contesting histories of colonial and apartheid rule in varied ways. In particular, it focuses on several tensions that emerged within three modes of material-discursive practice within the production of the LHP: (...) subject recruitment, informed consent, and participant reflections. In the end, it argues that several contradictory tensions were central to the making of the LHP’s postapartheid genome and that it should be understood as nonracial rather than antiracist. (shrink)

Studies about women’s underrepresentation in the U.S. science, technology, engineering, and mathematics academic workforce have flourished in the past decade. Much of this research focuses on institutionalized gender barriers and implicit biases, consistent with theorizing about how work organizations disproportionately benefit men, white people, and other systemically advantaged groups. But to what extent do faculty most likely disadvantaged by systematic inequities actually perceive “barriers” to equity in the context of their own work lives? What might the repercussions associated with variation (...) in perceptions about inequity be, especially within institutions of higher education actively pursuing equity agendas under such programs as the National Science Foundation’s ADVANCE program? Using interview data from 53 STEM women faculty working at a university that received a 5-year NSF ADVANCE IT award, we examine the range of views held among women scientists about the extent to which opportunity and success are a function of meritocratic versus nonmeritocratic processes. Findings show that almost a third of participants held the view that opportunities and advancement are primarily a function of meritocratic processes. We discuss implications of these findings for broader institutional efforts to reduce inequities in academic STEM. (shrink)

Two central assumptions of current models of language acquisition were addressed in this study: (1) knowledge of linguistic structure is "mapped onto" earlier forms of non-linguistic knowledge; and (2) acquiring a language involves a continuous learning sequence from early gestural communication to linguistic expression. The acquisition of the first and second person pronouns ME and YOU was investigated in a longitudinal study of two deaf children of deaf parents learning American Sign Language (ASL) as a first language. Personal pronouns in (...) ASL are formed by pointing directly to the addressee (YOU) or self (I or ME), rather than by arbitrary symbols. Thus, personal pronouns in ASL resemble paralinguistic gestures that commonly accompany speech and are used prelinguistically by both hearing and deaf children beginning around 9 months. This provides a means for investigating the transition from prelinguistic gestural to linguistic expression when both gesture and language reside in the same modality.\nThe results indicate that deaf children acquired knowledge of personal pronouns over a period of time, displaying errors similar to those of hearing children despite the transparency of the pointing gestures. The children initially (ages 10 and 12 months) pointed to persons, objects, and locations. Both children then exhibited a long avoidance period, during which one function of the pointing gesture (pointing to self and others) dropped out completely. During this period their language and cognitive development were otherwise entirely normal, and they continued to use other types of pointing (e.g., to objects). When pointing to self and others returned, it was marked with errors typical of hearing children; one child exhibited consistent pronoun reversal errors, thinking the YOU point referred to herself, while the other child exhibited reversal errors inconsistently. Evidence from experimental tasks conducted with the first child revealed that pronoun errors occurred in comprehension as well. Full control of the ME and YOU pronouns was not achieved until 25-27 months, around the same time when hearing children master these forms. Thus, the study provides evidence for a discontinuity in the child's transition from prelinguistic to linguistic communication. It is argued that aspects of linguistic structure and its acquisition appear to involve distinct, language-specific knowledge. (shrink)

: Although "brain death" and the dead donor rule—i.e., patients must not be killed by organ retrieval—have been clinically and legally accepted in the U.S. as prerequisites to organ removal, there is little data about public attitudes and beliefs concerning these matters. To examine the public attitudes and beliefs about the determination of death and its relationship to organ transplantation, 1351 Ohio residents ≥18 years were randomly selected and surveyed using random digit dialing (RDD) sample frames. The RDD telephone survey (...) was conducted using computer-assisted telephone interviews. The survey instrument was developed from information provided by 12 focus groups and a pilot study of the questionnaire. Three scenarios based on hypothetical patients were presented: "brain dead," in a coma, or in a persistent vegetative state (PVS). Respondents provided personal assessments of whether the patient in each scenario was dead and their willingness to donate that patient's organs in these circumstances. More than 98 percent of respondents had heard of the term "brain death," but only one-third (33.7%) believed that someone who was "brain dead" was legally dead. The majority of respondents (86.2%) identified the "brain-dead" patient in the first scenario as dead, 57.2 percent identified the patient in a coma as dead (Scenario 2), and 34.1 percent identified the patient in a PVS as dead (Scenario 3). Nearly one-third (33.5%) were willing to donate the organs of patients they classified as alive for at least one scenario, in seeming violation of the dead donor rule. Most respondents were not willing to violate the dead donor rule, although a substantial minority was. However, the majority of respondents were unaware, misinformed, or held beliefs that were not congruent with current definitions of "brain death." This study highlights the need for more public dialogue and education about "brain death" and organ donation. (shrink)

This article contributes to Construction Grammar, historical linguistics, and Russian linguistics through an in-depth corpus study of predicate agreement in constructions with quantified subjects. Statistical analysis of approximately 39,000 corpus examples indicates that these constructions constitute a network of constructions (“allostructions”) with various preferences for singular or plural agreement. Factors pull in different directions, and we observe a relatively stable situation in the face of variation. We present an analysis of a multidimensional network of allostructions in Russian, thus contributing to (...) our understanding of allostructional relationships in Construction Grammar. With regard to historical linguistics, language stability is an understudied field. We illustrate an interplay of divergent factors that apparently resists language change. The syntax of numerals and other quantifiers represents a notoriously complex phenomenon of the Russian language. Our study sheds new light on the contributions of factors that favor singular or plural agreement in sentences with quantified subjects. (shrink)

I propose that human experience of matter provides the source domain for the metaphor that motivates the grammatical category of aspect in Russian. This model is a version of the universal TIME IS SPACE metaphor, according to which SITUATIONS ARE MATERIAL ENTITIES, and, more specifically, PERFECTIVE IS A DISCRETE SOLID OBJECT versus IMPERFECTIVE IS A FLUID SUBSTANCE. The contrast of discrete solid objects with fluid substances reveals a rich array of over a dozen properties; the isomorphism observed between those properties (...) and the complex uses of aspect in Russian is compelling. This model presents a more finely articulated account of Russian aspect than feature analysis can achieve. Although some of these properties overlap significantly with the count versus mass distinction often associated with aspect, the properties provide more detail and ground the metaphor to concrete experience. Properties of matter can be divided into three groups: inherent properties such as edges, shape, and integrity (which correspond to inherent situation aspect); interactional properties such as juxtaposition, dynamism, and salience (which correspond to discourse phenomena of aspect); and human interactional properties such as graspability and impact (which correspond to pragmatic phenomena of aspect). The interactional and human interactional properties can be used to motivate subjective construal, whereas the inherent properties serve as default motivators. The model will be demonstrated in detail using Russian data, followed by a survey comparing Russian with the other Slavic languages, which will show that deviations consist of either non-implementation of a given property, or the implementation of an inherent (default) property in place of an interactional or human interactional property. This model will be contrasted with a brief discussion of a selection of non-Slavic languages. The specific metaphor in this model does not apply beyond Slavic, but perhaps it will encourage investigation into the source domain of aspect in other languages. There appears to be a correlation between the relatively heavy morphological investment Slavic languages make in nominal individuation and the individuation of situations presented in this metaphorical model. (shrink)

Background Intensivists must provide enough analgesia and sedation to ensure dying patients receive good palliative care. However, if it is perceived that too much is given, they risk prosecution for committing euthanasia. The goal of this study is to develop consensus guidelines on analgesia and sedation in dying intensive care unit patients that help distinguish palliative care from euthanasia. Methods Using the Delphi technique, panelists rated levels of agreement with statements describing how analgesics and sedatives should be given to dying (...) ICU patients and how palliative care should be distinguished from euthanasia. Participants were drawn from 3 panels: 1) Canadian Academic Adult Intensive Care Fellowship program directors and Intensive Care division chiefs (N = 9); 2) Deputy chief provincial coroners (N = 5); 3) Validation panel of Intensivists attending the Canadian Critical Care Trials Group meeting (N = 12). Results After three Delphi rounds, consensus was achieved on 16 statements encompassing the role of palliative care in the intensive care unit, the management of pain and suffering, current areas of controversy, and ways of improving palliative care in the ICU. Conclusion Consensus guidelines were developed to guide the administration of analgesics and sedatives to dying ICU patients and to help distinguish palliative care from euthanasia. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:IntroductionStuart J. Youngner (bio), Laura A. Siminoff (bio), and Renie Schapiro (bio)This issue of the Kennedy Institute of Ethics Journal (KIEJ) centers on a piece of empirical research. The motivation behind the study of Laura Siminoff, Christopher Burant, and Stuart Youngner (2004) was to find out more about what the general public understands and believes about when a person is dead. More specifically, the study tried to (...) determine how members of the public define death, especially their acceptance and interpretation of the medical concept of "brain death," and their attitudes toward the so-called "dead donor rule," an informal but powerful social and legal norm insisting that the taking of organs for transplantation not cause the death of the source of those organs.As the demand for organs increases and the waiting list grows, the United States has explored multiple ways to expand the pool of potential donors. One approach has been to gerrymander (coherently or not) the line between life and death to shift patients who are extremely compromised but traditionally considered to be in the living category into the dead category. In this way, the dead donor rule remains technically intact. This reasoning is explicit in the report of the Harvard Medical School Ad Hoc Committee (1968) that "introduced" "brain death" to the American culture. Since then, other efforts to redraw the line have been proposed and rejected.One alternative to gerrymandering is to consider under what conditions, if any, it is morally acceptable to violate the dead donor rule. Some would argue that this alternative is the more "honest" approach. Rather than sidestepping moral problems by calling people dead, it brings the moral problems to the surface where the necessity of sticking to the rule can be considered on its own merits. However, when the Journal of the American Medical Association printed a position paper that proposed making anencepahlic newborns an exception to the dead donor rule, along with arguments about why this was acceptable, the outcry was so great that the proposal was retracted (AMA 1995).Clearly, our society has identified organ transplantation as a priority, although two papers in this volume (those by Courtney Campbell and by Megan Crowley-Matoka and Robert Arnold) take issue with that prioritization. The fact that the donor pool has remained relatively stable (and inadequate) despite massive efforts [End Page 211] to increase it speaks, at least in part, to the cultural and legal resistance to "new" ways to procure more organs. Voluntarism seems to have peaked. Financial incentives clash with the heavily endorsed notion of the "gift of life" and seem to many to violate the dignity of the human body. Presumed consent or eminent domain, in which the community has a greater claim to a person's organs than that person or his/her family, go against the grain of American individual freedom and the ethos of patient autonomy.Abandoning the dead donor rule generally is regarded as an even tougher sell to the American public and its legislators. The study by Siminoff and colleagues attempts, among other things, to gauge just how tough this sell would be. What the data actually demonstrate is a matter of interpretation, and this issue of the KIEJ is devoted to some of those interpretations. The authors, with the exception of Daniel Hausman, came together for a meeting in Cleveland, Ohio, during which the study's methods and data were presented with time for questions, clarifications, and general discussion. The authors then worked with the editors to generate the papers printed in this volume.The issue begins with a presentation of the study conducted by Siminoff and colleagues. The same paper also appears in the journal Social Science and Medicine, where it includes the conclusions of the authors (Siminoff, Burant, and Youngner 2004). In the current volume, we present only the methodology of and data from the study, allowing a number of distinguished commentators to offer their own conclusions and reflections.The first response comes from Tracy Schmidt, Executive Director of Intermountain Donor Services, one of our nation's organ procurement organizations (OPOs). For years, organ procurement professionals have reported anecdotal stories about families who wished to donate organs of... (shrink)

Medical advances in transplantation techniques have driven an exponential increase in the demand for transplantable organs. Unfortunately, policy efforts to bolster the organ supply have been less than effective, failing to provide a stopgap for ever-increasing numbers of patients who await organ transplantation. The number of registrations on waiting lists exceeded 65,245 in early 1999, a 325% increase over the 20,000 that existed 11 years earlier in 1988. Regrettably, more than 4,000 patients die each year while awaiting transplantation.

Gendered barriers to women’s advancement in STEM disciplines are subtle, often the result of gender practices, gender stereotypes, and gendered occupational cultures. Professional socialization into scientific cultures encourages and rewards gender practices that help to maintain gendered barriers. This article focuses more specifically on how individual women scientists’ gender practices potentially sustain gender barriers. Findings based on interview data from thirty women in academic STEM fields reveal that women draw on gendered expectations and norms within their disciplines to discursively distance (...) themselves from other women they perceive as having deviated from such norms and expectations. The types of distancing in which these respondents engage reflect and support gendered structures, cultures, and practices that ultimately disadvantage women and obscure gender inequality. I conclude by discussing the implications of women scientists’ distancing practices for efforts to change the gendered cultures of STEM disciplines. (shrink)

: This paper reviews current and suggested policies designed to increase organ donation in the United States and indicates the problems inherent to these approaches for increasing organ donation by African Americans. Data from a population-based study assessing attitudes and beliefs about organ donation among white and African-American respondents are presented and discussed. We pose the question of whether it is reasonable to maintain the existing system or whether we should institute a system that uses policies based on the attitudes (...) and beliefs of a minority group that is in greater need than the majority. In light of the discussion, we suggest that the current policies guiding the organ procurement system are not adequate to address existing concerns within the African-American community and that a different set of assumptions may be needed to drive organ procurement policy. (shrink)

The relationship between construal and redundancy has not been previously explored empirically. Russian aspect allows speakers to construe situations as either Perfective or Imperfective, but it is not clear to what extent aspect is determined by context and therefore redundant. We investigate the relationship between redundancy and open construal by surveying 501 native Russian speakers who rated the acceptability of both Perfective and Imperfective verb forms in complete extensive authentic contexts. We find that aspect is largely redundant in 81% of (...) uses, and in 17% of contexts aspect is relatively open to construal. We contend that anchoring in redundant contexts likely facilitates the independence of construal in contexts with less redundancy. However further research is needed to discover what makes contexts redundant since known cues for aspect are absent in the majority of such contexts. Native speakers are fairly consistent in giving the original aspect high ratings, but less consistent in rating the non-original aspect, indicating potential problems in testing the reactions of speakers to non-authentic data. (shrink)

Uncertainty about the acceptability of the forest industry and its practices to the citizens of Mississippi provided the impetus for a study of the attitudes and perceptions of eight constituency groups toward the forest industry in the state. This study examines attitudes and perceptions of two of those groups, loggers and two environmentalists/conservationists, and finds similarities and differences. Survey data analysis finds that all groups hold similar perceptions of themes defining the forest industry and forest industry occupations but differ concerning (...) activities the industry does or does not perform well and environmental problems associated with the forest industry. Mississippi Loggers Association members hold more positive attitudes/perceptions, similar to those of the Mississippi Wildlife Federation. Attitudes/perceptions of Mississippi 2020, a small grassroots organization, differ from Mississippi Loggers Association members in all instances and from Mississippi Wildlife Federation members on some issues. (shrink)

Hundreds of thousands of individuals experience traumatic injuries each year. Some are mild to moderate in nature and patients experience full functional recovery and little change to their physical appearance. Others result in enduring, if not permanent, changes in physical functioning and appearance. Reconstructive plastic surgical procedures are viable treatments options for many patients who have experienced the spectrum of traumatic injuries. The goal of these procedures is to restore physical functioning and reduce the psychosocial burden of living with an (...) appearance that may be viewed negatively by the patient or by others. Even after receipt of reconstructive procedures, many patients are left with residual disfigurement. In some, disability and disfigurement may be so profound that individuals are candidates for vascularized composite allotransplantation procedures, i.e., the transplantation of a vascularized human body part containing multiple tissue types as an anatomical and/or structural unit. This narrative review paper summarizes the literature on the psychosocial burden experienced by those who have visible disfigurement. While many of these individuals experience stigma and discrimination, relatively few studies have employed a stigma framework to understand the psychosocial sequelea. This paper briefly addresses this framework. Last, particular focus is given to the psychosocial issues of individuals with particularly severe injuries who are potential candidates for VCA procedures. (shrink)

In the dominant metaphor for organ transplantation, the organ is the ultimate gift, the dying donor's life‐giving bequest, conveyed and made possible by a heroic transplant team. The metaphor encourages donation and enforces recipients’ compliance with post‐transplant treatment. It is also inaccurate and sometimes deeply damaging for the recipient.

A foundational goal of cognitive linguistics is to explain linguistic phenomena in terms of general cognitive strategies rather than postulating an autonomous language module (Langacker 1987: 12–13). Metonymy is identified among the imaginative capacities of cognition (Langacker 1993: 30, 2009: 46–47). Whereas the majority of scholarship on metonymy has focused on lexical metonymy, this study explores the systematic presence of metonymy in word-formation. I argue that in many cases, the semantic relationships between stems, affixes, and the words they form can (...) be analyzed in terms of metonymy, and that this analysis yields a better, more insightful classification than traditional descriptions of word-formation. I present a metonymic classification of suffixal word-formation in three languages: Russian, Czech, and Norwegian. The system of classification is designed to maximize comparison between lexical and word-formational metonymy. This comparison supports another central claim of cognitive linguistics, namely that grammar (in this case word-formation) and lexicon form a continuum (Langacker 1987: 18–19), since I show that metonymic relationships in the two domains can be described in nearly identical terms. While many metonymic relationships are shared across the lexical and grammatical domains, some are specific to only one domain, and the two domains show different preferences for source and target concepts. Furthermore, I find that the range of metonymic relationships expressed in word-formation is more diverse than what has been found in lexical metonymy. There is remarkable similarity in word-formational metonymy across the three languages, despite their typological differences, though they all show some degree of language-specific behavior as well. Although this study is limited to three Indo-European languages, the goal is to create a classification system that could be implemented (perhaps with modifications) across a wider spectrum of languages. (shrink)

We introduce a novel paradigm for studying the cognitive processes used by listeners within interactive settings. This paradigm places the talker and the listener in the same physical space, creating opportunities for investigations of attention and comprehension processes taking place during interactive discourse situations. An experiment was conducted to compare results from previous research using videotaped stimuli to those obtained within the live face-to-face task paradigm. A headworn apparatus is used to briefly display LEDs on the talker’s face in four (...) locations as the talker communicates with the participant. In addition to the primary task of comprehending speeches, participants make a secondary task light detection response. In the present experiment, the talker gave non-emotionally-expressive speeches that were used in past research with videotaped stimuli. Signal detection analysis was employed to determine which areas of the face received the greatest focus of attention. Results replicate previous findings using videotaped methods. (shrink)

Transplantation experiments have shown that developing metazoan organs carry intrinsic information about their size and shape. Organ and body size are also sensitive to extrinsic cues provided by the environment, such as the availability of nutrients. The genetic and molecular pathways that contribute to animal size and shape are numerous, yet how they cooperate to control growth is mysterious. The recent identification and characterization of several mutations affecting growth in Drosophila melanogaster promises to provide insights. Many of these mutations affect (...) the extrinsic control of animal size; others affect the organ‐intrinsic control of pattern and size. In this review, we summarize the characteristics of some of these mutations and their roles in growth and size control. In addition, we speculate about possible connections between the extrinsic and intrinsic pathways controlling growth and pattern. BioEssays 24:54–64, 2002. © 2002 John Wiley & Sons, Inc. (shrink)

The fifth edition of this classic introduction to Christian ethics via the case method approach, utilizing case studies of contemporary ethical issues.